Figure S1.
Electrophysiology protocols used and NaV1.6 inactivation. (A) Shown are illustrations of the voltage-step protocols used in experimental work. (B) 100 nM GrTX-SIA does not influence the inactivation rate of NaV1.6. Representative current traces at −30 and −10 mV are shown before (black) and after (red) a 4-min incubation period with 100 nM GrTX-SIA. A single exponential fit of the inactivation phase yielded a time constant (τ) that is plotted against its voltage step in the right panel. Circles represent mean ± standard error of the mean (SEM) of n = 6 oocytes.

Electrophysiology protocols used and Na V 1.6 inactivation. (A) Shown are illustrations of the voltage-step protocols used in experimental work. (B) 100 nM GrTX-SIA does not influence the inactivation rate of NaV1.6. Representative current traces at −30 and −10 mV are shown before (black) and after (red) a 4-min incubation period with 100 nM GrTX-SIA. A single exponential fit of the inactivation phase yielded a time constant (τ) that is plotted against its voltage step in the right panel. Circles represent mean ± standard error of the mean (SEM) of n = 6 oocytes.

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