Figure 5.
Cnn is required for Arp2/3 pathway accumulation at the nascent cap. (A) Corner brackets show Rac-GTP sensor at telophase 11 nascent cap in control and Cnn RNAi. Nascent cap position is determined by imaging into interphase when abnormally small compartments form with Cnn RNAi (turquoise brackets). (B and C) Corner brackets show SCAR-NG and Arp3-GFP at telophase 11 nascent caps with control and Cnn RNAi. (D) Enrichment assay and data comparing nascent caps versus middle surface of telophase compartment. Embryo values plotted.

Cnn is required for Arp2/3 pathway accumulation at the nascent cap. (A) Corner brackets show Rac-GTP sensor at telophase 11 nascent cap in control and Cnn RNAi. Nascent cap position is determined by imaging into interphase when abnormally small compartments form with Cnn RNAi (turquoise brackets). (B and C) Corner brackets show SCAR-NG and Arp3-GFP at telophase 11 nascent caps with control and Cnn RNAi. (D) Enrichment assay and data comparing nascent caps versus middle surface of telophase compartment. Embryo values plotted.

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