Figure S6.

Comparisons of IGS-derived non-coding RNA in SETX knock-out compared to control cells: view of entire IGS region. IGV view of the entire rDNA IGS showing positive- and negative-strand reads in the control and SETX knock-out cells. Reads mapped to the human ribosomal DNA complete repeat unit (Genebank U13369.1) were divided by their orientation (plus or minus). Annotations of the IGS and repeat elements were shown on the top. The arrow bar indicates the location where the 3′ part of the PAPAS (promoter and pre-rRNA antisense) extends to. Reads were down-sampled to 100 reads if the maximum depth is over 100. Plus: sense strand of rDNA; Minus: antisense strand of rDNA.

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