Characterization of the T cells circulating in patients with primary UMs. (A) Example of CD4 versus CD8 expression in T (CD3+) cells in the peripheral blood (left) and frequency of the indicated cell populations in patients with D3 or M3 UM tumors stratified according to CMV status (right). (B) Example of CD127 versus CD25 staining in CD4+ T cells in the blood (left) and frequency of the indicated populations in D3 or M3 patients (right). (C) Example of CD45RA versus CD27 staining. Frequency of effector (CD27−), naïve (CD45RA+CD27+), and memory (CD45RA−CD27+) among CD4+ (left) or CD8+ (right) T cells. A two-way ANOVA was performed and is displayed below the relevant panel.