SKs, such as BIN2, are pivotal in integrating various signaling pathways, responses to extracellular cues. According to Wiese et al. (5), the integration of signals and decision-making processes occurs at the interface between AtSK and TRAPPII. Downstream of TRAPPII, Rab GTPases play a crucial role in executing decisions. The phosphorylation status of AtTRS120 may modulate TRAPPII GEF activity, affecting the function of its cognate Rabs. PM: plasma membrane; P enclosed in green circle: phosphate group; Rab scwitch regions (I [red] and II [green]) are indicated.