FXRs, but not SGs, are involved in DMV biogenesis, related to Fig. 1 . (A) Transcriptional levels of FXR2 are much lower than FXR1 and FMR1 in HeLa cells. Quantitative data are presented as mean ± SD (n = 3). (B) GFP-FXR1, FXR2-GFP, and GFP-FMR1 concentrate at Nsp3/4⁺ foci in Nsp3/4-overexpressing cells. GFP-FXR1, FXR2-GFP, and GFP-FMR1 show diffuse cytoplasmic localization under control conditions. Images are representative of at least 10 cells. Bars: 5 μm; insets, 2 μm. (C) The schematic shows the domain organization of FXR1, FXR2, and FMR1. (D) Immunostaining with anti-G3BP shows that G3BP does not colocalize with Nsp3/4⁺ puncta in cells treated without or with arsenite. Images are representative of at least 10 cells. Bars: 5 μm; insets, 2 μm.