NR-V04 has minimal toxicity. (A–F) Hematology analysis of different blood cell components after NR-V04 or vehicle treatment. NR-V04 did not cause significant changes in the hematologic profile including (A) mean platelet volume, (B) hemoglobin, (C) mean corpuscular hemoglobin, (D) mean corpuscular hemoglobin concentration, (E) hematocrit, and (F) mean corpuscular volume. N = 3, P > 0.05 for A–F, one experiment. A two-sided unpaired t test was performed, with all P values > 0.05. Supplementary to Fig. 9.