(Related to Fig. 4 ): Examples of DNA fiber images of the total DNA staining experiments performed the DNA combing, spreading, and hybrid spreading techniques. (A) Images collected with DNA combing. The numbers 1 and 2 denote the examples of blue–green–blue and blue–green fibers shown in Fig. 4 A. (B) Images collected with DNA spreading. The numbers 1 and 2 denote the examples of blue–green–blue and blue–green fibers shown in Fig. 4 A. (C) Images collected with the hybrid spreading technique. The numbers 1 and 2 denote the examples of blue–green–blue and blue–green fibers shown in Fig. 4 F.