Related to Fig. 3 . Ultrastructural organization of the epidermis and dermal–epidermal junction in mTurq2-Col4a1/+ embryonic skin. (A–D) Representative TEM images from additional experimental replicates of E18.5 WT control (A and B) and mTurq2-Col4a1/+ (C and D) embryonic skin. Der = dermis, BL = basal layer, SL = spinous layer, GL = granular layer, SC = stratum corneum. The dotted line denotes dermal–epidermal boundary. Scale bars, 10 µm. (E–H) Representative images of individual hemidesmosomes at the dermal–epidermal junction region of WT control (E and F) and mTurq2-Col4a1/+ (G and H) embryonic skin. HD = hemidesmosome, PM = plasma membrane, BM = basement membrane. Scale bars, 250 nm.