Decreasing PE level contributes to the cytotoxicity of PTDSS1i-treated Ramos cells. (A and B) Major phospholipid composition (A) and dead cell accumulation (B) of parental Ramos cells and PTDSS2-KO clone cultured in the indicated condition. The cells were cultured in the medium containing PTDSS1i (100 nM) and/or ethanolamine hydrochloride (0.1 mM) for 96 h, and then subjected to the analysis. Statistical P values examined based on Welch’s t test are shown.