Slug loss in keratinocytes results in decreased Dsg1. (A) Microarray data shows an increase in Dsg1 expression in primary human keratinocytes upon loss of Slug expression, as well as a concurrent decrease in CXCL1 expression. (B) siRNA knockdown of Slug causes an increase in Dsg1 protein levels as seen by Western blot. n = 3. *P < 0.05, **P < 0.01. Student’s t test. (C) Slug knockdown levels assessed by Western blot, corresponding to experiment in Fig. 3, I and J. Source data are available for this figure: SourceData FS3.