ANT steady-state flux analysis. We analyzed the dependence on the fluxes through ANTs at constant concentrations of adenine nucleotides in the different compartments and at a constant membrane potential of 180 mV. We analyzed how the flux changes with the driving forces of the cycles (Eq. 33). (A) ADPi − ATPm net flux through ANTs for different ATP to ADP ratios in the matrix. (B) ADPi − ATPm net flux through ANTs for different ratios of ATP and ADP in the IMS.
Figure 4.

ANT steady-state flux analysis. We analyzed the dependence on the fluxes through ANTs at constant concentrations of adenine nucleotides in the different compartments and at a constant membrane potential of 180 mV. We analyzed how the flux changes with the driving forces of the cycles (Eq. 33). (A) ADPi − ATPm net flux through ANTs for different ATP to ADP ratios in the matrix. (B) ADPi − ATPm net flux through ANTs for different ratios of ATP and ADP in the IMS.

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