![Qualitative reproduction of the experimental results from published work (Duyckaerts et al., 1980). (A and B) Reciprocal of the initial rate of ADP exchange as a function of the reciprocal of the external ADP concentration. The initial rate was measured for 3 external-ADP concentrations and 11 internal-ADP concentrations (only four are shown). The lines were calculated by the method of least squares. Experimental data reproduced from (A) Duyckaerts et al. (1980) and (B) our simulations. (C and D) Reciprocal of the initial rate of ADP exchange as a function of the reciprocal of the internal-ADP concentration. The initial rate was measured for 3 external ADP concentrations and 11 internal-ADP concentrations. Data reproduced from (C) Duyckaerts et al. (1980) and (D) our simulations. (E and F) Reciprocal of the initial rate of ADP exchange as a function of the reciprocal of [ADP]i[ADP]o. Data reproduced from (E) Duyckaerts et al. (1980), the parameter value KAB is 26.5 × 10−3 mM2, and (F) our simulations; our estimation of KAB from our simulations is 27.06 × 10−3 mM2.](https://cdn.rupress.org/rup/content_public/journal/jgp/155/9/10.1085_jgp.202213263/1/jgp_202213263_figs2.png?Expires=1767671371&Signature=vnoaIoJDuLMdr4TbJPjhLgSsvl0AFA4MygAjVcPY3oYMT7C2Sa9DmqmGsvb8qOQ~JRRQWXG8V0jfcGi9jRRsAJ9WoMta-Nt0P7~fRAyTt47Mg15bLLPX9pqfbufSmMh~cpJfrAGrb06JEhTsmX6pK4hjWlCiHnSSs6vl7GwjPRxb5Ty5hSHHiqVNUswc2ZbVQBAPuSqNOuW-jRTKwln0dPySx6PvCWTm2rrdShxQHG1QDK-ql~-TrSCiSTnCr6Sqe~dNI4PMPSzuKpZuwZAPVMC4m6nRH5lA5othXwHwLae33zsH1xLKb5PeMf3HByUf~OufxOzVdV~pFNgjo7cGeQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Qualitative reproduction of the experimental results from published work ( Duyckaerts et al., 1980 ). (A and B) Reciprocal of the initial rate of ADP exchange as a function of the reciprocal of the external ADP concentration. The initial rate was measured for 3 external-ADP concentrations and 11 internal-ADP concentrations (only four are shown). The lines were calculated by the method of least squares. Experimental data reproduced from (A) Duyckaerts et al. (1980) and (B) our simulations. (C and D) Reciprocal of the initial rate of ADP exchange as a function of the reciprocal of the internal-ADP concentration. The initial rate was measured for 3 external ADP concentrations and 11 internal-ADP concentrations. Data reproduced from (C) Duyckaerts et al. (1980) and (D) our simulations. (E and F) Reciprocal of the initial rate of ADP exchange as a function of the reciprocal of [ADP]i[ADP]o. Data reproduced from (E) Duyckaerts et al. (1980), the parameter value KAB is 26.5 × 10−3 mM2, and (F) our simulations; our estimation of KAB from our simulations is 27.06 × 10−3 mM2.