Figure 1.
Efflux of 14C-urea from human RBC under SE conditions at 25°C, pH 7.2, 1 mM urea. The logarithmic ordinate expresses the fraction of radioactive isotope that remains in the cells at a given time. The negative slope of the curves equals the rate coefficient k (s−1) that is used to calculate the urea permeability Pu (cm/s). The two donors represent the variation of urea transport. The experiments were performed with the continuous flow tube technique. Pu is, respectively, 0.54 (SD ± 0.03, n = 4) × 10−4 cm/s (D13) and 3.2 (SD ± 0.6, n = 4) × 10−4 cm/s (D12).

Efflux of 14C-urea from human RBC under SE conditions at 25°C, pH 7.2, 1 mM urea. The logarithmic ordinate expresses the fraction of radioactive isotope that remains in the cells at a given time. The negative slope of the curves equals the rate coefficient k (s−1) that is used to calculate the urea permeability Pu (cm/s). The two donors represent the variation of urea transport. The experiments were performed with the continuous flow tube technique. Pu is, respectively, 0.54 (SD ± 0.03, n = 4) × 10−4 cm/s (D13) and 3.2 (SD ± 0.6, n = 4) × 10−4 cm/s (D12).

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