Larger head groups allow for more and simultaneous interactions. Each residue is shown with the percent of time it is interacting with the PUFA throughout the simulation. (A) Representation of constant binders of LIN-Gly in Site Iα. (B) Representation of constant binders of LIN-Gly and LIN-Tyr in Site Iβ. (C) Representation of constant binders of LIN-Gly and LIN-Tyr in Site II.