LIN-Gly and LIN-Tyr interact with many residues on the KCNQ1 channel. Contact analysis for AA LIN-Gly and LIN-Tyr simulations. The gray highlighted boxes in the background indicate the position of the transmembrane helices. (A) Histogram and heat map of total interaction time of each residue in KCNQ1 for LIN-Tyr and LIN-Gly in the Site I and Site II systems. (B) Histogram and heat map of longest lifetime interactions of each residue in KCNQ1 for LIN-Tyr and LIN-Gly in the Site I and Site II systems.