Figure 9.
![Figure 9. NFA decreases rectification of ISlo2.1. (A) Average ISlo2.1-V relationships in oocytes treated sequentially with 1, 2, and 3 mM NFA (n = 8). (B) Average ISlo2.1-V relationships in another batch of oocytes treated sequentially with 4, 5, and 6 mM NFA (n = 6). Extracellular solution was K104. (C) G-V relationships for ISlo2.1 for different concentrations of NFA as indicated. (D) Shift in V1/2 of the G-V relationship (filled circles) and minimum value of G/Gmax (open squares) is [NFA] dependent. Data were fitted with a Hill equation (smooth curves). For shift in V1/2, EC50 = 2.1 ± 0.2 mM and nH = 2.9 ± 0.1 (R2 = 1.0). For minimum G/Gmax, EC50 = 2.4 ± 0.2 mM and nH = 1.9 ± 0.3 (R2 = 0.93).](https://cdn.rupress.org/rup/content_public/journal/jgp/135/3/10.1085_jgp.200910316/6/jgp_200910316_rgb_fig9.jpeg?Expires=1767805648&Signature=cMfexlYeXsKNTT6HE8KoQWzM6ya0fF7MNbZ~wy9BCL3T4iWTlBKNj4DUWNWbJ8MYWUW129HQACYZ54E8qmTzPZuyhKV59jhDZk3iO1LxwE5PTFStkqwBiPIWXQ0S4i9TD7zMNkoVksj2aoseqV0DXK-yvNwpxPP8U7wGKv6a3bypC8gxIkdieZsEDMWW1EAckQFU-noWcGdG5F~6HkW4GjzE7UnAhV1URI4e2C8sd2RQSZqlt-mR0W2U1-IwZqpa30-Gh0nQCGfNuxkyNdguu~Ehn51ICLBqdTpbUMvQ3AYGYNxBvAZIElqqnpBSlQBzvyDC~eK~kJz28bAgBBiyDg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
NFA decreases rectification of ISlo2.1. (A) Average ISlo2.1-V relationships in oocytes treated sequentially with 1, 2, and 3 mM NFA (n = 8). (B) Average ISlo2.1-V relationships in another batch of oocytes treated sequentially with 4, 5, and 6 mM NFA (n = 6). Extracellular solution was K104. (C) G-V relationships for ISlo2.1 for different concentrations of NFA as indicated. (D) Shift in V1/2 of the G-V relationship (filled circles) and minimum value of G/Gmax (open squares) is [NFA] dependent. Data were fitted with a Hill equation (smooth curves). For shift in V1/2, EC50 = 2.1 ± 0.2 mM and nH = 2.9 ± 0.1 (R2 = 1.0). For minimum G/Gmax, EC50 = 2.4 ± 0.2 mM and nH = 1.9 ± 0.3 (R2 = 0.93).
