Figure 3.
![Figure 3. Increased [Na+]i blocks outward ISlo2.1 at positive potentials. (A) Currents recorded from an oocyte expressing Slo2.1 under control conditions (a) after 8-min treatment with 1 mM NFA (b), after 25-min incubation in Nai-loading solution (c), and then after 8-min treatment with 0.1 mM NFA (d). Vt was varied from −160 to +80 mV and applied in 40-mV increments. (B) I-V relationships for the oocyte under the indicated conditions.](https://cdn.rupress.org/rup/content_public/journal/jgp/135/3/10.1085_jgp.200910316/6/jgp_200910316_lw_fig3.jpeg?Expires=1767727695&Signature=QAAOyPjtSGsbUV6eRc9G4yg3hYa0GAC0jfhuBQmSMAAXszdcTYrgadYa6U62zVTvJx8UhQUSWYcKl0qZTBNZ8XwBkX89GmIJEMeHMGV7bY9F97hd4Px-ldHvdslBW3l0LDe0j67N5ccfs-Arb4RyJyIgmkCNLQ0Ag72hVnwjpTwgyPGGIjMJEALwVC2g6HGOTfDcs6uUIZExg9qOOgas7EXTWnfpmOMXoTrI8p9ZNLwGG9Hg0-AYtMcWGvt26Gb0azgTnTzERf4~Agez40bx-eEk5bKlrK9IK6Rak9-a-op~e-fGR2zLpn4AYfYJX4TyOAJkg~H~QgQmBJLqvqavIg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Increased [Na+]i blocks outward ISlo2.1 at positive potentials. (A) Currents recorded from an oocyte expressing Slo2.1 under control conditions (a) after 8-min treatment with 1 mM NFA (b), after 25-min incubation in Nai-loading solution (c), and then after 8-min treatment with 0.1 mM NFA (d). Vt was varied from −160 to +80 mV and applied in 40-mV increments. (B) I-V relationships for the oocyte under the indicated conditions.
