Figure 5.
![Figure 5. Neutralization of E636 reduces proton inhibition. (A) Representative single-channel currents from the E636Q mutant channel at different external pHs in symmetrical 1-M KCl solutions. Holding potential was either +60 mV (top row) or −60 mV (bottom row). (B and C) Plots of unitary current amplitudes versus [K+] at the indicated pHo. (B) Vh = −60 mV. (C) Vh = +60 mV. (D and E) Similar plots for wild type were shown for comparison.](https://cdn.rupress.org/rup/content_public/journal/jgp/134/3/10.1085_jgp.200910255/6/jgp_200910255_rgb_fig5.jpeg?Expires=1767712013&Signature=xbMZWJZ9WkJJBRelwST6m7v8GXA8oAdy4vomdxmMdgNFjrUnZWYejZst6FOlrREd-MnK42D6mCzkWMuigf23YX17pC7cJ3jTBWxeIXgIPpBo7MHXHL4m~MR7dStJbdUu60z4Q7~vtexRI-352Hl6AXgSvpzvfUJqOf66FcKQO2f~IfDwdySvlsuTO0wEoqBA3gch3fCm1PR-h1plzAg1veGoAs2vPxtGjhlLHhFlzvkHl70bRrgAMoWkJDVtdsLL5MaY2GI7Fa8yYIMOtBgtHFLitYZAxcDlvfQbdcUfRNxO-QP1HsqAsu1vNaooPzDJ1qXtcmVCXfLf~oQCP~TlkA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Neutralization of E636 reduces proton inhibition. (A) Representative single-channel currents from the E636Q mutant channel at different external pHs in symmetrical 1-M KCl solutions. Holding potential was either +60 mV (top row) or −60 mV (bottom row). (B and C) Plots of unitary current amplitudes versus [K+] at the indicated pHo. (B) Vh = −60 mV. (C) Vh = +60 mV. (D and E) Similar plots for wild type were shown for comparison.
