Figure 5.
Figure 5. Effects of CaVβ isoforms on calcium inactivation stem from underlying effects on VDI. Normalized inactivation curves measured at +20 mV for (A) CaV1.2 and (B) CaV1.2 GGG subunits coexpressed with CaVβ1, CaVβ2a, CaVβ2b, or in the absence of CaVβ. (Left) VDI is shown and is reproduced for comparison from the first 300 ms of Fig. 3 (A and B). (Middle) Inactivation in calcium. (Right) netCDI.

Effects of CaVβ isoforms on calcium inactivation stem from underlying effects on VDI. Normalized inactivation curves measured at +20 mV for (A) CaV1.2 and (B) CaV1.2 GGG subunits coexpressed with CaVβ1, CaVβ2a, CaVβ2b, or in the absence of CaVβ. (Left) VDI is shown and is reproduced for comparison from the first 300 ms of Fig. 3 (A and B). (Middle) Inactivation in calcium. (Right) netCDI.

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