Figure 12.
Effect of apical bath CO2 on basolateral membrane Na/nHCO3 cotransporter. Low HCO3 (2.62 mM) Ringer was perfused into the basal bath to record the initial control response, and this maneuver was repeated in (A) 13% or (B) 1% apical bath CO2. After returning to control Ringer, low basal bath [HCO3]-induced control response was obtained. Solid bars above the graphs represent solution changes from control Ringer as described in the legend to Fig. 2.