Figure 4.
HCO3− fluxes across the apical membrane of interlobular pancreatic ducts isolated from wild-type and ΔF mice. Membrane potential–evoked changes in pHi in interlobular pancreatic ducts isolated from wild-type (A) and ΔF/ΔF (B) mice. Experiments were performed in the bilateral absence of Cl− following a similar protocol to that used in the guinea pig duct experiment shown in Fig. 2 A. Each trace is a representative of four experiments.