Figure 9.
Lack of effects of antagonists of store-operated currents on Islow. (A) 50 µM SKF96365 was continuously pressure-ejected by a puffer pipette, beginning shortly after the slow current had peaked (horizontal line). There was no discernible alteration in the time course of the current, indicating that Islow was not suppressed. Vh = −50 mV; light intensity of 28.6 × 1015 × photons × cm−2 × s−1). (B) A large-amplitude Islow elicited in the presence of 1 mM La3+ (applied by extensive bath superfusion before applying the light stimulus). Vh = −60 mV; light intensity of 2.39 × 1015 photons × cm−2 × s−1).