Figure 1.
Figure 1. The homotetrameric Shaker quadruple mut R362Q/R365Q/R368N/R371Q expresses poorly at the plasma membrane in Xenopus oocytes. (A) Ionic current (top) and confocal image (bottom) of a typical oocyte injected with VENUS-Shaker zH4 IR (monomers). (B) Ionic current (top) and confocal image (bottom) of a typical oocyte injected with the VENUS-Shaker quadruple mut R362Q/R365Q/R368N/R371Q (monomers). Cut-open voltage clamp measurements. The internal and external solutions contained 120 and 12 mM K+, respectively.

The homotetrameric Shaker quadruple mut R362Q/R365Q/R368N/R371Q expresses poorly at the plasma membrane in Xenopus oocytes. (A) Ionic current (top) and confocal image (bottom) of a typical oocyte injected with VENUS-Shaker zH4 IR (monomers). (B) Ionic current (top) and confocal image (bottom) of a typical oocyte injected with the VENUS-Shaker quadruple mut R362Q/R365Q/R368N/R371Q (monomers). Cut-open voltage clamp measurements. The internal and external solutions contained 120 and 12 mM K+, respectively.

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