Figure 5.
Figure 5. Effects of nonhydrolyzable ATP analogue and protein phosphatase inhibitors on the BHK cell capacitance response and exchange current rundown. (A) Capacitance, conductance, and current records from a BHK cell perfused with 2 mM AMP-PNP for 4 min before activating exchange current. (B) Capacitance changes and peak exchange current densities for control cells, cells perfused with 2 mM AMP-PNP, cells perfused with 2 mM AMP-PNP, and with 5 μM cyclosporin for 4 min before activating exchange current, and cells perfused with AMP-PNP with 9 mM pyrophosphate and 4 mM fluoride.

Effects of nonhydrolyzable ATP analogue and protein phosphatase inhibitors on the BHK cell capacitance response and exchange current rundown. (A) Capacitance, conductance, and current records from a BHK cell perfused with 2 mM AMP-PNP for 4 min before activating exchange current. (B) Capacitance changes and peak exchange current densities for control cells, cells perfused with 2 mM AMP-PNP, cells perfused with 2 mM AMP-PNP, and with 5 μM cyclosporin for 4 min before activating exchange current, and cells perfused with AMP-PNP with 9 mM pyrophosphate and 4 mM fluoride.

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