Figure 5.
Figure 5. Inhibition of RYR2 activity by luminal Mg2+ in the presence of 3 μM cytoplasmic Ca2+. The traces were taken from a single experiment, and the luminal [Mg2+] is shown at the left of each trace. The cytoplasmic bath contained 2 mM ATP and 3 μM Ca2+, and the luminal bath contained 0.1 mM Ca2+. The dashed lines depict the closed current level in each trace.

Inhibition of RYR2 activity by luminal Mg2+ in the presence of 3 μM cytoplasmic Ca2+. The traces were taken from a single experiment, and the luminal [Mg2+] is shown at the left of each trace. The cytoplasmic bath contained 2 mM ATP and 3 μM Ca2+, and the luminal bath contained 0.1 mM Ca2+. The dashed lines depict the closed current level in each trace.

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