Figure 6.
![Figure 6. Simulated effect of RyR block. The near-SL and near-SR cytosolic [Ca2+] and APs are shown from simulations of (A) spontaneous and (B) electrically excited activity. The RyR block was applied after three control E–C coupling cycles.](https://cdn.rupress.org/rup/content_public/journal/jgp/132/4/10.1085_jgp.200809961/7/jgp_200809961_rgb_fig6.jpeg?Expires=1767745283&Signature=ooCMawbb3KlqKQzXDjUG~iG9kaeMqACNnvVkbsDvwlrvv5oq8-elA1eJJ3FY7qK2W7drDWC1zhkvp8THfKQ3ZSPh3xZuaH1pcpaTsggxzaMAmDWepdRmcNt~MgJAOEuHgOsj0wvrOPX1AnO5nQYGBqoqV4cB0KiwNY3NsYNIyE9MESUCe32iUxG5sezty1y2YhDjmtFpqFlzuNC~-x~9aACK06-7PU0t9MJia2~ncLRhqhszqhQjPUt-zjYiE4QrtUCRkoETx8LaQIpNk8T56Bm9~KAG~bCCNh0d23WupLMSSoGZmaoI7MpBFg5t3EaAC8OlO4hSpmhPVA1PopYMpQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Simulated effect of RyR block. The near-SL and near-SR cytosolic [Ca2+] and APs are shown from simulations of (A) spontaneous and (B) electrically excited activity. The RyR block was applied after three control E–C coupling cycles.
