Figure 5.
![Figure 5. The resting potential windows favoring spontaneous Ca2+ activity and Ca2+ activity generated by electrical pacing. A constant current from 4 to −2.5 pA/pF with 0.25 pA/pF intervals was applied to the model cell to adjust the r.p. of the model cell to values between −107 and −27 mV. At each r.p. value, the spontaneous and paced (0.25, 0.5, and 1 Hz) cytosolic Ca2+ activity was observed for 10 s after 40 s of stabilization of the model. The figure shows the average amplitudes spontaneously evoked and electrically stimulated cytosolic [Ca2+] transients at given frequency.](https://cdn.rupress.org/rup/content_public/journal/jgp/132/4/10.1085_jgp.200809961/7/jgp_200809961_rgb_fig5.jpeg?Expires=1767742537&Signature=D2hFbWvS3AReXM7JE4Duia9dv1ICWTnALf~vxOVpLmrlhe4Mc7Q1dHcQOy-EVc2gDdsM7TjG3xc-MB6CypI5Ni9TAKVLe36SnpOnHOxSdMmTbCzd7UIXvc0C5a0Kz4EJLYjXJZhfzvtvBgl0RW~7ZWrAMH~9f8RM8aIrlqnWtGgTyErLiRzTp~rHTWNw4nuNXxUPYN-WbTlHksQkyqF-ZIji153M8Wxm53mxTrFyOeCvhFkw0QDNh3RL5OgASyfbMIjaQ6J5r7LyP2MlLiCUGUIQ~P804oksdKh8w-QF2nsg7cDKycQ2xXHt6wK2Xe7TUP85EJS4Oa38HDqqqCy~6g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
The resting potential windows favoring spontaneous Ca2+ activity and Ca2+ activity generated by electrical pacing. A constant current from 4 to −2.5 pA/pF with 0.25 pA/pF intervals was applied to the model cell to adjust the r.p. of the model cell to values between −107 and −27 mV. At each r.p. value, the spontaneous and paced (0.25, 0.5, and 1 Hz) cytosolic Ca2+ activity was observed for 10 s after 40 s of stabilization of the model. The figure shows the average amplitudes spontaneously evoked and electrically stimulated cytosolic [Ca2+] transients at given frequency.
