Figure 1.

Measurement of isoproterenol-induced cAMP signals near the plasma membrane of HEK-293 cells. HEK-293 cells were infected with CNG-channels that transduce cAMP signals to electrical current. Responses were elicited by exposure of each cell to the indicated concentrations of isoproterenol. Shown are cAMP signals in response to 20 nM (A), 50 nM (B), and 1 μM (C) isoproterenol. All traces are representative of the range of responses from at least five experiments.

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