(A) Illustrations of the bare region arrangements of myosin filament profiles in a simple lattice (left) and a superlattice (right). The simple lattice has identically oriented triangular profiles throughout. The superlattice has two filament orientations with an irregular, statistical arrangement. (B–D) The different effects of the simple lattices and superlattices on the myosin head arrangements on the three 14.3-nm spaced crowns of myosin heads within the 42.9-nm repeat that occurs along vertebrate muscle myosin filaments. Each radiating line from the myosin filament backbones (blue) represents a pair of myosin heads. On crown 1 the simple lattice has three head pairs approaching one of the actin filaments (brown) and no heads approaching the other actin filament in the unit cell. On the other hand the superlattice spreads the myosin heads more evenly along the actin filaments so that on crown 1 there are two head pairs for one actin filament and one head pair for the second filament. Similar effects occur on crowns 2 and 3.