Figure 6.
![Figure 6. Lanthanum and Mg2+ sensitivity and relative cation permeabilities of the ORCa, GTL-1, and GON-2 channels. (A) Dose–response relationship for the inhibitory effect of extracellular La3+ on IORCa, IGTL-1, and IGON-2. Data were fit using the equation I = 1/1 + ([La3+]/IC50)n. Values are means ± SEM (n = 4–6). (B) Relative cation permeabilities of the ORCa, GTL-1, and GON-2 channels. Values are means ± SEM (n = 4–9). (C) Dose–response relationship for the inhibitory effect of intracellular Mg2+ on IORCa, IGTL-1, and IGON-2. Data were fit using the equation I = 1/1 + ([Mg2+]/IC50)n. Values are means ± SEM (n = 4–8). IGTL-1 and IGON-2 are currents measured in intestinal cells isolated from gon-2 and gtl-1 mutant worms, respectively.](https://cdn.rupress.org/rup/content_public/journal/jgp/131/3/10.1085_jgp.200709914/6/245fig6.jpeg?Expires=1767809353&Signature=Ol0vkiy4ZO0w56cGMTOgEs1YhPa30ot~YNVC3gj6RsknoGZdC0jlJAycWrA6hM0r~yR~Rq3tMC16OlyzWIB-t0iMik~J8M98fnEgOxG4pQfPi~PU-HMtBJqR3Zt3uOcLAiOVt8uUCfwXYh5XHryuMiu0msHl5yXIiTWP8~a0EhiDpboYBx4SXMp2r3gDm6b~s403HXk9N4QSUTPt3jSg2pee1WoTIoSJqsMPp2rK-tJzwwGtLOVxLNqNaj400RIf5HfdHovKML8EaWI~LPiGiSQHRpIOR~suS6~q~NzgywXydP23gtbwDv1PmxSVBBrxaRg9xYTX0qZ616Pxt3lFUg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Lanthanum and Mg2+ sensitivity and relative cation permeabilities of the ORCa, GTL-1, and GON-2 channels. (A) Dose–response relationship for the inhibitory effect of extracellular La3+ on IORCa, IGTL-1, and IGON-2. Data were fit using the equation I = 1/1 + ([La3+]/IC50)n. Values are means ± SEM (n = 4–6). (B) Relative cation permeabilities of the ORCa, GTL-1, and GON-2 channels. Values are means ± SEM (n = 4–9). (C) Dose–response relationship for the inhibitory effect of intracellular Mg2+ on IORCa, IGTL-1, and IGON-2. Data were fit using the equation I = 1/1 + ([Mg2+]/IC50)n. Values are means ± SEM (n = 4–8). IGTL-1 and IGON-2 are currents measured in intestinal cells isolated from gon-2 and gtl-1 mutant worms, respectively.
