Figure 5.

Current-to-voltage characteristics of IORCa, IGTL-1, and IGON-2. (A) Representative whole cell currents recorded from wild-type, gtl-1 mutant, and gon-2 mutant worm intestinal cells. Currents were elicited by stepping membrane voltage from −80 to +80 mV in 20-mV steps from a holding potential of 0 mV. (B) Relative current-to-voltage relationships of IORCa, IGTL-1, and IGON-2. Values are means ± SEM (n = 9–22). *, P < 0.001, compared with IORCa. IGTL-1 and IGON-2 are currents measured in intestinal cells isolated from gon-2 and gtl-1 mutant worms, respectively.

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