Temperature dependence of fusion pores. The kinetic scheme at the top indicates the formation of a closed fusion pore, C, and the transition to the open state, O. The open state can close with rate k_c or enter the dilating phase, D, with rate k_d. Arrhenius plots are presented for (A) foot amplitude, (B) 1/(mean foot duration), (C) k_c, and (D) k_d. k_c and k_d were determined from the mean lifetime (Fig. 6 B) and fraction of large kiss-and-run events (Fig. 5 C) as described in the text and in Wang et al. (2006).