Figure 2.
Figure 2. The plot of theoretical versus experimental permeability for different lipids should ideally fall on the diagonal magenta line. For the open squares, PC was assumed to be infinite. The red circles show the best fit to Eq. 3 and the green triangles show the best fit when the hydrocarbon thickness is reduced by δ = 15 Å. The fitted values of A0 are shown in the figure legend. The lipids all have phosphatidylcholine (PC) headgroups with two acylated hydrocarbon chains. DMPC and DLPC have saturated chains with 14 and 12 carbons, respectively. DOPC and diC22:1PC have monounsaturated chains with 18 and 22 carbons, respectively. POPC has a palmitic acid chain with 16 carbons in the sn-1 position and a monounsaturated oleoyl chain in the sn-2 position. The experimental permeabilities at 30°C are from Mathai et al. (2007).

The plot of theoretical versus experimental permeability for different lipids should ideally fall on the diagonal magenta line. For the open squares, PC was assumed to be infinite. The red circles show the best fit to Eq. 3 and the green triangles show the best fit when the hydrocarbon thickness is reduced by δ = 15 Å. The fitted values of A0 are shown in the figure legend. The lipids all have phosphatidylcholine (PC) headgroups with two acylated hydrocarbon chains. DMPC and DLPC have saturated chains with 14 and 12 carbons, respectively. DOPC and diC22:1PC have monounsaturated chains with 18 and 22 carbons, respectively. POPC has a palmitic acid chain with 16 carbons in the sn-1 position and a monounsaturated oleoyl chain in the sn-2 position. The experimental permeabilities at 30°C are from Mathai et al. (2007).

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