Figure 1.
Induction of BALT after mucosal infection with MVA. (A–H) C57/BL6 mice were infected i.n. with 107 IU MVA, and at the time points indicated (days after infection), lung sections were analyzed by fluorescence microscopy applying mAb and DAPI as indicated. Representative sections from three to six mice analyzed for each time point derived from two to three different experiments are shown. Bars, 100 µm. (I) The number of BALT structures per entire central lung section was determined by microscopy (means + SD; n = 3–5 animals per time point; pooled data are derived from six independent experiments). b, bronchioles; v, vessels.
