Figure 6.
EBF1 and PAX5 Gene Targets. Microarray analysis of leukemia samples from progenitor B cells from C57BL/6 (LMC) mice (n = 5), Stat5b-CA nonleukemic mice (n = 4), and Stat5b-CA x Ebf1+/− mice (n = 5). Cluster analysis was performed using gene lists from previously published tables of PAX5 or EBF1 gene targets. The heatmap on the left represents all of the genes, regardless of significance, and the enlarged region contains the genes that were significant by ANOVA analyses (P < 0.01) and displayed a twofold difference in expression from LMC cells (n = 5). The analysis was performed as described in the Materials and methods.