Figure 4. MyD88 deficiency sensitizes and TNFR1 deficiency reduces experimental colitis in A20IEC-KO mice. (A) Clinical score of A20IEC-KOMyD88-deficient mice (n = 4) and control A20IEC-KOMyD88 heterozygous mice (n = 4) treated with 1.5% DSS. (B) Clinical score of double A20IEC-KOMyD88-deficient mice (n = 4) and single MyD88 knockout mice (n = 4) treated with 1.5% DSS. (C) Clinical score of A20IEC-KOTNFR1-deficient mice (n = 10) and control A20IEC-KOTNFR1 heterozygous mice (n = 5) treated with 1.5% DSS. (D) Clinical score of double A20IEC-KOTNFR1-deficient mice (n = 10) and single TNFR1 knockout mice (n = 7) treated with 1.5% DSS. Error bars represent SEM. *, P < 0.05. Data are representative of two independent experiments.
Figure 4.

MyD88 deficiency sensitizes and TNFR1 deficiency reduces experimental colitis in A20IEC-KO mice. (A) Clinical score of A20IEC-KOMyD88-deficient mice (n = 4) and control A20IEC-KOMyD88 heterozygous mice (n = 4) treated with 1.5% DSS. (B) Clinical score of double A20IEC-KOMyD88-deficient mice (n = 4) and single MyD88 knockout mice (n = 4) treated with 1.5% DSS. (C) Clinical score of A20IEC-KOTNFR1-deficient mice (n = 10) and control A20IEC-KOTNFR1 heterozygous mice (n = 5) treated with 1.5% DSS. (D) Clinical score of double A20IEC-KOTNFR1-deficient mice (n = 10) and single TNFR1 knockout mice (n = 7) treated with 1.5% DSS. Error bars represent SEM. *, P < 0.05. Data are representative of two independent experiments.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal