Figure 5. Ear skin cytokine levels 24 h after 4 or 15 UVB exposures. Levels of IL-10 (A), IL-4 (B), IL-6 (C), and TNF (D) in lysates of control ears not treated with UVB irradiation (– UVB) or ears treated with 4 or 15 exposures to 2 kJ/m2 UVB irradiation in WBB6F1-Kit+/+ (WT) mice, mast cell–deficient WBB6F1-KitW/W-v (KitW/W-v) mice, WT BMCMC→KitW/W-v mice, and VDR−/− BMCMC→KitW/W-v mice. Data (n = 6–8 per group) are from the two experiments performed, each of which gave similar results, in which three to four mice/group were tested per experiment. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001 for the indicated comparisons.
Figure 5.

Ear skin cytokine levels 24 h after 4 or 15 UVB exposures. Levels of IL-10 (A), IL-4 (B), IL-6 (C), and TNF (D) in lysates of control ears not treated with UVB irradiation (– UVB) or ears treated with 4 or 15 exposures to 2 kJ/m2 UVB irradiation in WBB6F1-Kit+/+ (WT) mice, mast cell–deficient WBB6F1-KitW/W-v (KitW/W-v) mice, WT BMCMC→KitW/W-v mice, and VDR−/− BMCMC→KitW/W-v mice. Data (n = 6–8 per group) are from the two experiments performed, each of which gave similar results, in which three to four mice/group were tested per experiment. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001 for the indicated comparisons.

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