Figure 5.
OX86 intratumor injection eradicates tumors of different hystotypes. N2C and TSA BALB/c mammary carcinomas, and MCA203 C57BL/6 fibrosarcoma of 3–4 mm in size received intratumor injection of 100 μg of purified rat IgG (left) or anti-OX40 (right). Tumor volume was calculated as longest diameter × (shortest diameter)2 (in cubic millimeters). Lines represent the tumor growth kinetics in each single mouse. The number of tumor-free mice out of the total number of treated mice is indicated. One representative of two independent experiments is shown.
