Figure 9. Summary of Notch2-induced cell cycle entry. RBP-Jκ–dependent transcription leads to accumulation of cyclin D1 in the cytosol. Notch ICD regulates entry into the cell cycle by controlling nuclear localization of cyclin D1 independently of RBP-Jκ.
Figure 9.

Summary of Notch2-induced cell cycle entry. RBP-Jκ–dependent transcription leads to accumulation of cyclin D1 in the cytosol. Notch ICD regulates entry into the cell cycle by controlling nuclear localization of cyclin D1 independently of RBP-Jκ.

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