Figure 2.
Figure 2. Inhibition of protein synthesis by RGS2. (A) The effects of 4 µM purified RGS proteins on the synthesis of the reference luciferase protein were examined in a reticulocyte-based in vitro translation assay as described in Materials and methods. (B) Concentration response effects of full-length RGS proteins on steady-state, agonist-stimulated GTPase activity of M1 muscarinic receptor–activated Gα11 as described in Materials and methods. The data are presented as mean ± SEM of three independent experiments performed in triplicate. *, P < 0.05 versus control (one-sample t test).

Inhibition of protein synthesis by RGS2. (A) The effects of 4 µM purified RGS proteins on the synthesis of the reference luciferase protein were examined in a reticulocyte-based in vitro translation assay as described in Materials and methods. (B) Concentration response effects of full-length RGS proteins on steady-state, agonist-stimulated GTPase activity of M1 muscarinic receptor–activated Gα11 as described in Materials and methods. The data are presented as mean ± SEM of three independent experiments performed in triplicate. *, P < 0.05 versus control (one-sample t test).

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