Figure 6.

ACTCCo/KO mice perform as well as or better than wild-type mice (and other genotypes tested) for grip strength, rotarod, and running wheel tests. (A–F) Mouse performance is given as measured by rotarod (A), grip strength (B), and running wheel analysis (mean speed [C], maximum speed [D], time spent running [E], and distance traveled [F]). n = 10, 11, or 12 for all groups of male 4–6-mo-old mice. Error bars represent ±SEM. *, P < 0.05; and **, P < 0.001 when ACTCCo/KO mice were compared with all other genotypes.

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