Effects of Pld overexpression in photoreceptors with altered Arf6 activity. (A) Representation of the activity states of Arf6 and the enzymes that convert Arf6 between these states. Arf6-GTP, GTP-bound Arf6; Arf1-GDP, GDP-bound Arf6. (B–D) TEM analysis of photoreceptors from wild-type (B), Arf6^−/− (C), and overexpressing Pld in Arf6^−/− (D). (E–G) Overexpressing schizo alone (E), Pld alone (F), and schizo + Pld (G). (H and I) Quantitative analysis of rhabdomere biogenesis defects in the aforementioned genotypes. Bar, 2 µm.