Figure 1.

Genes elevated in developing Tsc1 eye-antennal tissue. (A) Transcriptional changes observed in Tsc1 eye-antennal imaginal discs grouped by proposed biological function. Included are genes whose expression was elevated at least 1.5-fold (P < 0.05) in Tsc1 tissue compared with the wild type. (B–E) Third instar larval eye imaginal discs; anterior is shown on the right. Arrowheads indicate the morphogenetic furrow. Activity of aay (B and C) and 4e-bp (D and E) enhancer trap lines in tissue misexpressing Gal4 (B and D) or Rheb (C and E) under control of the GMR promoter. Bar, 50 μM.

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