Deletion of Tmod1 depresses skeletal muscle contractile function. (A and B) Muscle PCSA (A) and slack sarcomere length (B) are unchanged in Tmod1^−/−Tg+ mice. (C and D) Isometric force (C) and isometric stress (D) produced by EDL muscle from Tmod1^−/−Tg+ mice are significantly decreased. *, P < 0.05; ***, P < 0.001. n = 8 muscles/genotype. Data are mean ± SEM.