Figure 3.
Figure 3. Condensins I and II are redundantly required for ES cell proliferation. (A) Morphology of ES cell colonies depleted of NcapD2, NcapD3, both NcapD2 and -D3, or Smc2. (B) Proportion of apoptotic (TUNEL+) ES cells depleted of condensin complexes as in A. (C) Proportion of apoptotic (TUNEL+) E14 ES cells or iMEFs upon mitotic arrest by nocodazole (noc) treatment. (B and C) Means and standard deviations of triplicate samples are shown. Bars, 120 µm.

Condensins I and II are redundantly required for ES cell proliferation. (A) Morphology of ES cell colonies depleted of NcapD2, NcapD3, both NcapD2 and -D3, or Smc2. (B) Proportion of apoptotic (TUNEL+) ES cells depleted of condensin complexes as in A. (C) Proportion of apoptotic (TUNEL+) E14 ES cells or iMEFs upon mitotic arrest by nocodazole (noc) treatment. (B and C) Means and standard deviations of triplicate samples are shown. Bars, 120 µm.

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