FOCAL POINT (Left to right) Francis Barr, Ricardo Nunes Bastos, Ulrike Gruneberg, and Kang Zeng find that the phosphatase PP6 regulates mitotic spindle assembly by limiting the kinase activity of Aurora A. Cells lacking PP6 (far right) show disorganized spindles (green) and misaligned chromosomes (red) due to unchecked Aurora A activity, which results in chromosome mis-segregation.

PHOTO COURTESY OF ANDREAS GERONDOPOULOS

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