The involvement of myosin V in filopodial rotation. (A and B) The y axis represents the filopodial angular velocity (A) or the filopodial velocity (B) in growth cones that express the indicated transgene products. Positive and negative values of the angular velocity indicate right- and left-screw rotation, respectively. Numbers in parentheses indicate the total number of growth cones examined. Data represent mean ± SEM. *, P < 0.05; **, P < 0.01; ***, P < 0.001 (Bonferroni’s multiple comparison test).