Figure 1.

Schematic representation of the seven canonical ERAD substrates used in this study. BACE476, CD3-δ, NHKBACE, and NHKCD3δ are type I membrane proteins (ERAD-LM substrates); BACE476Δ, CD3-δΔ, and NHK are the corresponding soluble ERAD-LS substrates.

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