Zhx2 weakens IL-15–promoted NK cell function. Splenic NK cells from Zhx2+/+ and Zhx2Δ/Δ mice were stimulated with PMA with or without the presence of STAT5-Inh (10 mM; representative of two independent experiments). (A and B) FACS plots and graphs show the mean fluorescence intensity of AKT phosphorylation (A) and percentage of CD107a- and IFN-γ–expressing NK cells (B). Error bars represent SEM per group in one experiment. Data were analyzed using Student’s t test (two-tailed paired t test). **, P < 0.0001; ***, P < 0.001.
Figure S3.

Zhx2 weakens IL-15–promoted NK cell function. Splenic NK cells from Zhx2+/+ and Zhx2Δ/Δ mice were stimulated with PMA with or without the presence of STAT5-Inh (10 mM; representative of two independent experiments). (A and B) FACS plots and graphs show the mean fluorescence intensity of AKT phosphorylation (A) and percentage of CD107a- and IFN-γ–expressing NK cells (B). Error bars represent SEM per group in one experiment. Data were analyzed using Student’s t test (two-tailed paired t test). **, P < 0.0001; ***, P < 0.001.

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